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Three of these intermediates, termed pre-B act , B act -I and B act -II, contain the complete NTR complex and three components of the NTC complex (CDC5L, CWC15 and PLRG1), whereas additional NTC components (PRP19, BCAS2) are not yet integrated 16

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4Department of Cell Biology and Genetics, Faculty of Science, University of Lagos, Akoka 100213, Lagos State, Nigeria

as in the case of the elevated mRNA, the basal bioavailable selenium may become the limiting factor for the efficient translation, whereas in the case of the elevated bioavailable selenium, the basal mRNA levels of seleno-GPxs may become the limiting factor for the overall increase of the protein activity